This is a pretty interesting article actually that details a study showing that not exercise for as little we a week can have negative implications on cognitive skills as well as memory.
Activity increases blood flow which carries oxygen and fuel to the brain during it and also after it.
Now be sure that this isn't exclusive to gym training or otherwise, I would assume that any activity beyond a moderate level would be adequate so if you're on holiday then 1 single session for 20 - 30mins would be suffice to keep your brain well and truly oiled!
Check it out in detail:
http://www.nytimes.com/2016/09/28/well/move/after-just-10-days-of-rest-brain-benefits-of-exercise-diminish.html?smid=fb-nytimes&smtyp=cur&_r=1
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